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Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue

BACKGROUND: In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transplant could be an alternative in patients with poor glycemic control, but ineffic...

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Detalles Bibliográficos
Autores principales: Jara, Claudia, Oyarzun-Ampuero, Felipe, Carrión, Flavio, González-Echeverría, Esteban, Cappelli, Claudio, Caviedes, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409404/
https://www.ncbi.nlm.nih.gov/pubmed/32774470
http://dx.doi.org/10.1186/s13098-020-00573-9