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The dual functions of α-tubulin acetylation in cellular apoptosis and autophage induced by tanespimycin in lung cancer cells

BACKGROUND: Reversible acetylation of α-tubulin has been implicated in modulating microtuble structures and functions, which may subsequently involve in cellular apoptosis and autophage. But how to trigger apoptosis or autophage at what level of acetylated α-tubulin (Ac-α-tubulin) are not known. Thi...

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Detalles Bibliográficos
Autores principales: Wang, Qilin, Liu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409415/
https://www.ncbi.nlm.nih.gov/pubmed/32774163
http://dx.doi.org/10.1186/s12935-020-01453-y