Germline RAD54L with somatic POLE defect implicated in Hypermutation phenotype: case report

BACKGROUND: Colorectal cancer is one of the most frequent causes of death among cancer patients. Hypermutated CRC is an extraordinary case of cancer, but curable if detected at early stages. However, the mechanism for developing a hypermutated CRC remains unclear. An association between RAD54L germl...

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Detalles Bibliográficos
Autores principales: Zohud, Bisan Abdalfatah, Wang, Meiling, Cai, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409428/
https://www.ncbi.nlm.nih.gov/pubmed/32758138
http://dx.doi.org/10.1186/s12876-020-01403-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409428/
https://www.ncbi.nlm.nih.gov/pubmed/32758138
http://dx.doi.org/10.1186/s12876-020-01403-y

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