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The 3D8 single chain variable fragment protein suppresses Newcastle disease virus transmission in transgenic chickens

BACKGROUND: The 3D8 single chain variable fragment (scFv) is a mini-antibody sequence that exhibits independent nuclease activity against all types of nucleic acids. In this research, crossing a 3D8 scFv G1 transgenic rooster with wild-type hens produced 3D8 scFv G(2) transgenic chickens to evaluate...

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Detalles Bibliográficos
Autores principales: Byun, Sung June, Choi, Hoonsung, Sureshkumar, Shanmugam, Yuk, Seong-Su, Kwon, Jung-Hoon, Noh, Jin-Yong, Jung, Sun Keun, Kim, Jeom Sun, Oh, Keon Bong, Yang, Hyeon, Lee, Gunsup, Lee, Hwi-Cheul, Woo, Jae-Seok, Song, Chang-Seon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409462/
https://www.ncbi.nlm.nih.gov/pubmed/32762754
http://dx.doi.org/10.1186/s12917-020-02462-9