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Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase

BACKGROUND: The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. Alkylation of purine bases can hinder DNA replication and if unresolved would eventually result in cell death. DNA-3-methyladenine glycosylase (MAG) is responsible for the repa...

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Detalles Bibliográficos
Autores principales: Pinthong, Nattapon, Limudomporn, Paviga, Vasuvat, Jitlada, Adisakwattana, Poom, Rattaprasert, Pongruj, Chavalitshewinkoon-Petmitr, Porntip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409487/
https://www.ncbi.nlm.nih.gov/pubmed/32762689
http://dx.doi.org/10.1186/s12936-020-03355-w