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The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma
BACKGROUND: Multiple Myeloma (MM) is a hematological malignancy with genomic heterogeneity and poor survival outcome. Apart from the central role of genetic lesions, epigenetic anomalies have been identified as drivers in the development of the disease. METHODS: Alterations in the DNA methylome were...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409490/ https://www.ncbi.nlm.nih.gov/pubmed/32762714 http://dx.doi.org/10.1186/s13045-020-00933-y |