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Neurodegenerative changes in early- and late-onset cognitive impairment with and without brain amyloidosis

BACKGROUND: A substantial number of patients clinically diagnosed with Alzheimer’s disease do not harbor amyloid pathology. We analyzed the presence and extent of tau deposition and neurodegeneration in amyloid-positive (AD) and amyloid-negative (nonAD) ADNI subjects while also taking into account a...

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Detalles Bibliográficos
Autores principales: Stage, Eddie C., Svaldi, Diana, Phillips, Meredith, Canela, Victor Hugo, Duran, Tugce, Goukasian, Naira, Risacher, Shannon L., Saykin, Andrew J., Apostolova, Liana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409508/
https://www.ncbi.nlm.nih.gov/pubmed/32758274
http://dx.doi.org/10.1186/s13195-020-00647-w