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PDX models of human lung squamous cell carcinoma: consideration of factors in preclinical and co-clinical applications
BACKGROUND: Treatment of human lung squamous cell carcinoma (LUSC) using current targeted therapies is limited because of their diverse somatic mutations without any specific dominant driver mutations. These mutational diversities preventing the use of common targeted therapies or the combination of...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409653/ https://www.ncbi.nlm.nih.gov/pubmed/32762722 http://dx.doi.org/10.1186/s12967-020-02473-y |