Cargando…
Intramuscular injection of vectorized-scFvMC1 reduces pathological tau in two different tau transgenic models
With evidence supporting the prion-like spreading of extracellular tau as a mechanism for the initiation and progression of Alzheimer’s disease (AD), immunotherapy has emerged as a potential disease-modifying strategy to target tau. Many studies have proven effective to clear pathological tau specie...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409655/ https://www.ncbi.nlm.nih.gov/pubmed/32762731 http://dx.doi.org/10.1186/s40478-020-01003-7 |