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Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphoma

BACKGROUND: The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new cancers diagnosed as Non-Hodgkin lymphoma, finding new biomarkers for the treatmen...

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Detalles Bibliográficos
Autores principales: Townsend, Michelle H., Ence, Zac E., Cox, Taylor P., Lattin, John E., Burrup, Weston, Boyer, Michael K., Piccolo, Stephen R., Robison, Richard A., O’Neill, Kim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409661/
https://www.ncbi.nlm.nih.gov/pubmed/32782434
http://dx.doi.org/10.1186/s12935-020-01457-8