Cargando…

Evaluation of the upregulation and surface expression of hypoxanthine guanine phosphoribosyltransferase in acute lymphoblastic leukemia and Burkitt’s B cell lymphoma

BACKGROUND: The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new cancers diagnosed as Non-Hodgkin lymphoma, finding new biomarkers for the treatmen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Townsend, Michelle H., Ence, Zac E., Cox, Taylor P., Lattin, John E., Burrup, Weston, Boyer, Michael K., Piccolo, Stephen R., Robison, Richard A., O’Neill, Kim L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409661/ https://www.ncbi.nlm.nih.gov/pubmed/32782434 http://dx.doi.org/10.1186/s12935-020-01457-8

Ejemplares similares

Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase
por: Monzani, Paulo S, et al.
Publicado: (2007)

Crystal structures and inhibition of Trypanosoma brucei hypoxanthine–guanine phosphoribosyltransferase
por: Terán, David, et al.
Publicado: (2016)

Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine–Guanine Phosphoribosyltransferases
por: Glockzin, Kayla, et al.
Publicado: (2022)

Non-small-cell lung cancer cell lines A549 and NCI-H460 express hypoxanthine guanine phosphoribosyltransferase on the plasma membrane
por: Townsend, Michelle H, et al.
Publicado: (2017)

Novel Hypoxanthine Guanine Phosphoribosyltransferase Gene Mutations in Saudi Arabian Hyperuricemia Patients
por: Alanazi, Mohammed, et al.
Publicado: (2014)

Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies
por: Weagel, Evita G., et al.
Publicado: (2018)

Potential new biomarkers for endometrial cancer
por: Townsend, Michelle H., et al.
Publicado: (2019)

Molecular analysis of hypoxanthine guanine phosphoribosyltransferase (HPRT) gene in five Korean families with Lesch-Nyhan syndrome.
por: Kim, K. J., et al.
Publicado: (1997)

Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors
por: Glockzin, Kayla, et al.
Publicado: (2023)

Evaluating Iso-Mukaadial Acetate and Ursolic Acid Acetate as Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase Inhibitors
por: Opoku, Francis, et al.
Publicado: (2019)

The Housekeeping Gene Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) Regulates Multiple Developmental and Metabolic Pathways of Murine Embryonic Stem Cell Neuronal Differentiation
por: Kang, Tae Hyuk, et al.
Publicado: (2013)

Hypoxanthine-Guanine Phosphoribosyltransferase/adenylate Kinase From Zobellia galactanivorans: A Bifunctional Catalyst for the Synthesis of Nucleoside-5′-Mono-, Di- and Triphosphates
por: Acosta, Javier, et al.
Publicado: (2020)

Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer
por: Nguyen, Khue Vu
Publicado: (2021)

Characterization of in vivo somatic mutations at the hypoxanthine phosphoribosyltransferase gene of a human control population.
por: Burkhart-Schultz, K, et al.
Publicado: (1993)

Biomarker analysis and clinical relevance of TK1 on the cell membrane of Burkitt’s lymphoma and acute lymphoblastic leukemia
por: Weagel, Evita G, et al.
Publicado: (2017)

Hypoxanthine-guanine phosphoribosyltransferase and inosine 5′-monophosphate dehydrogenase activities in three mammalian species: aquatic (Mirounga angustirostris), semi-aquatic (Lontra longicaudis annectens) and terrestrial (Sus scrofa)
por: Barjau Pérez-Milicua, Myrna, et al.
Publicado: (2015)

Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome
por: Torres, Rosa J, et al.
Publicado: (2007)

Hypoxanthine guanine phosphoribosyltransferase 1, a target of miR-125b-5p, promotes cell proliferation and invasion in head and neck squamous cell carcinoma
por: Yuan, Li, et al.
Publicado: (2023)

Red Blood Cells from Individuals with Lesch–Nyhan Syndrome: Multi-Omics Insights into a Novel S162N Mutation Causing Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency
por: Reisz, Julie A., et al.
Publicado: (2023)

Correction to: Membrane expression of thymidine kinase 1 and potential clinical relevance in lung, breast, and colorectal malignancies
por: Weagel, Evita G., et al.
Publicado: (2019)

Hypoxanthine guanine phosphoribosyl transferases SmHGPRTases functional roles in Schistosoma mansoni
por: Batista, Izabella Cristina Andrade, et al.
Publicado: (2022)

Generation of hypoxanthine phosphoribosyltransferase gene knockout rabbits by homologous recombination and gene trapping through somatic cell nuclear transfer
por: Yin, Mingru, et al.
Publicado: (2015)

Plasma Hypoxanthine-Guanine Phosphoribosyl Transferase Activity in Bottlenose Dolphins Contributes to Avoiding Accumulation of Non-recyclable Purines
por: López-Cruz, Roberto I., et al.
Publicado: (2016)

KIF15 is involved in development and progression of Burkitt lymphoma
por: Wang, Zhao, et al.
Publicado: (2021)

Lack of Direct Involvement of 8‐Hydroxy‐2′‐deoxyguanosine in Hypoxanthine‐guanine Phosphoribosyltransferase Mutagenesis in V79 Cells Treated with N,N'‐Bis(2‐hydroxyperoxy‐2‐methoxyethyl)‐l,4,5,8‐naphthalenetetracarboxylic‐diimide (NP‐III) or Riboflavin
por: Nakajima, Madoka, et al.
Publicado: (2002)

Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria
por: Woodberry, Tonia, et al.
Publicado: (2009)

Histone deacetylase 6 activity is critical for the metastasis of Burkitt’s lymphoma cells
por: Ding, Ning, et al.
Publicado: (2014)

Novel monoclonal antibodies against thymidine kinase 1 and their potential use for the immunotargeting of lung, breast and colon cancer cells
por: Velazquez, Edwin J., et al.
Publicado: (2020)

High Frequency of Deletions at the Hypoxanthine‐guanine Phosphoribosyl‐transferase Locus in an Ataxia‐telangiectasia Lymphoblastoid Cell Line Irradiated with y‐Rays
por: Tachibana, Akira, et al.
Publicado: (2001)

Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD)
por: Yaku, Keisuke, et al.
Publicado: (2019)

Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety
por: Tichý, Tomáš, et al.
Publicado: (2012)

RNA helicase DHX15 decreases cell apoptosis by NF-κB signaling pathway in Burkitt lymphoma
por: Chen, Yuan, et al.
Publicado: (2022)

Hypoxanthine enhances the cured meat taste
por: Ichimura, Sayaka, et al.
Publicado: (2016)

The dual PI3K/mTOR inhibitor NVP-BEZ235 inhibits proliferation and induces apoptosis of burkitt lymphoma cells
por: Li, Chuntuan, et al.
Publicado: (2015)

Hypoxanthine Phosphoribosyl Transferase 1 Is Upregulated, Predicts Clinical Outcome and Controls Gene Expression in Breast Cancer
por: J. Sedano, Melina, et al.
Publicado: (2020)

Mutations increased overexpression of Notch1 in T-cell acute lymphoblastic leukemia
por: Lin, Chunlan, et al.
Publicado: (2012)

Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia
por: Huang, Xin, et al.
Publicado: (2015)

Thymidine Kinase 1 Upregulation Is an Early Event in Breast Tumor Formation
por: Alegre, Melissa M., et al.
Publicado: (2012)

Exercise training upregulates intracellular nicotinamide phosphoribosyltransferase expression in humans: a systematic review with meta-analysis
por: Sun, Xu, et al.
Publicado: (2023)

WP1130 reveals USP24 as a novel target in T-cell acute lymphoblastic leukemia
por: Luo, Hao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bc5sqsbijn4lq3ete5rs8bcgb8