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DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

BACKGROUND: Environmental pollution induces oxidative stress and apoptosis in mammalian oocytes, which can cause defects in reproduction; however, the molecular regulation of oxidative stress in oocytes is still largely unknown. In the present study, we identified that dynamin-related protein 1 (DRP...

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Detalles Bibliográficos
Autores principales: Zhang, Haolin, Pan, Zhennan, Ju, Jiaqian, Xing, Chunhua, Li, Xiaohan, Shan, Mengmeng, Sun, Shaochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409671/
https://www.ncbi.nlm.nih.gov/pubmed/32782788
http://dx.doi.org/10.1186/s40104-020-00489-4