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ACE2 enhance viral infection or viral infection aggravate the underlying diseases

ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' und...

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Detalles Bibliográficos
Autores principales: Teng, Shaolei, Tang, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409731/
https://www.ncbi.nlm.nih.gov/pubmed/32832038
http://dx.doi.org/10.1016/j.csbj.2020.08.002