ACE2 enhance viral infection or viral infection aggravate the underlying diseases

ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' und...

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Detalles Bibliográficos
Autores principales: Teng, Shaolei, Tang, Qiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409731/
https://www.ncbi.nlm.nih.gov/pubmed/32832038
http://dx.doi.org/10.1016/j.csbj.2020.08.002
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author Teng, Shaolei
Tang, Qiyi
author_facet Teng, Shaolei
Tang, Qiyi
author_sort Teng, Shaolei
collection PubMed
description ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' underlying diseases and ages. Therefore, particular care to the patients with underlying diseases is needed during the treatment of COVID-19 patients.
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spelling pubmed-74097312020-08-07 ACE2 enhance viral infection or viral infection aggravate the underlying diseases Teng, Shaolei Tang, Qiyi Comput Struct Biotechnol J Review Article ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' underlying diseases and ages. Therefore, particular care to the patients with underlying diseases is needed during the treatment of COVID-19 patients. Research Network of Computational and Structural Biotechnology 2020-08-06 /pmc/articles/PMC7409731/ /pubmed/32832038 http://dx.doi.org/10.1016/j.csbj.2020.08.002 Text en © 2020 The Authors. Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Teng, Shaolei
Tang, Qiyi
ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_full ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_fullStr ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_full_unstemmed ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_short ACE2 enhance viral infection or viral infection aggravate the underlying diseases
title_sort ace2 enhance viral infection or viral infection aggravate the underlying diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409731/
https://www.ncbi.nlm.nih.gov/pubmed/32832038
http://dx.doi.org/10.1016/j.csbj.2020.08.002
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