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Kinetic Heterogeneity of Cancer Cell Fractional Killing

Lethal drugs can induce incomplete cell death in a population of cancer cells, a phenomenon referred to as fractional killing. Here, we show that high-throughput population-level time-lapse imaging can be used to quantify fractional killing in response to hundreds of different drug treatments in par...

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Detalles Bibliográficos
Autores principales: Inde, Zintis, Forcina, Giovanni C., Denton, Kyle, Dixon, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409774/
https://www.ncbi.nlm.nih.gov/pubmed/32640215
http://dx.doi.org/10.1016/j.celrep.2020.107845