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Macrophage Immunometabolism and Inflammaging: Roles of Mitochondrial Dysfunction, Cellular Senescence, CD38, and NAD

Aging is a complex process that involves dysfunction on multiple levels, all of which seem to converge on inflammation. Macrophages are intimately involved in initiating and resolving inflammation, and their dysregulation with age is a primary contributor to inflammaging—a state of chronic, low-grad...

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Detalles Bibliográficos
Autores principales: Yarbro, Johnathan R., Emmons, Russell S., Pence, Brandt D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409778/
https://www.ncbi.nlm.nih.gov/pubmed/32774895
http://dx.doi.org/10.20900/immunometab20200026