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Metabolic Efficacy of Phosphate Prodrugs and the Remdesivir Paradigm
[Image: see text] Drugs that contain phosphates (and phosphonates or phosphinates) have intrinsic absorption issues and are therefore often delivered in prodrug forms to promote their uptake. Effective prodrug forms distribute their payload to the site of the intended target and release it efficient...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409933/ https://www.ncbi.nlm.nih.gov/pubmed/32821882 http://dx.doi.org/10.1021/acsptsci.0c00076 |