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A recombinant oncolytic Newcastle virus expressing MIP-3α promotes systemic antitumor immunity

BACKGROUND: The oncolytic Newcastle disease virus (NDV) is inherently able to trigger the lysis of tumor cells and induce the immunogenic cell death (ICD) of tumor cells and is also an excellent gene-engineering vector. The macrophage inflammatory protein-3α (MIP-3α) is a specific chemokine for dend...

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Detalles Bibliográficos
Autores principales: Huang, Feng-Ying, Wang, Jin-Yan, Dai, Shu-Zhen, Lin, Ying-Ying, Sun, Yan, Zhang, Liming, Lu, Zhuoxuan, Cao, Rong, Tan, Guang-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410001/
https://www.ncbi.nlm.nih.gov/pubmed/32759233
http://dx.doi.org/10.1136/jitc-2019-000330