Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy

Aberrant, neovascular retinal blood vessel growth is a vision-threatening complication in ischemic retinal diseases. It is driven by retinal hypoxia frequently caused by capillary nonperfusion and endothelial cell (EC) loss. We investigated the role of EC apoptosis in this process using a mouse mode...

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Detalles Bibliográficos
Autores principales: Grant, Zoe L., Whitehead, Lachlan, Wong, Vickie H.Y., He, Zheng, Yan, Richard Y., Miles, Abigail R., Benest, Andrew V., Bates, David O., Prahst, Claudia, Bentley, Katie, Bui, Bang V., Symons, Robert C.A., Coultas, Leigh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410052/
https://www.ncbi.nlm.nih.gov/pubmed/32427589
http://dx.doi.org/10.1172/JCI127668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410052/
https://www.ncbi.nlm.nih.gov/pubmed/32427589
http://dx.doi.org/10.1172/JCI127668

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