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Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy
Aberrant, neovascular retinal blood vessel growth is a vision-threatening complication in ischemic retinal diseases. It is driven by retinal hypoxia frequently caused by capillary nonperfusion and endothelial cell (EC) loss. We investigated the role of EC apoptosis in this process using a mouse mode...
Autores principales: | Grant, Zoe L., Whitehead, Lachlan, Wong, Vickie H.Y., He, Zheng, Yan, Richard Y., Miles, Abigail R., Benest, Andrew V., Bates, David O., Prahst, Claudia, Bentley, Katie, Bui, Bang V., Symons, Robert C.A., Coultas, Leigh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410052/ https://www.ncbi.nlm.nih.gov/pubmed/32427589 http://dx.doi.org/10.1172/JCI127668 |
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