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Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

GWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. Here, we aimed to assess DNA methylation impact on host genome in natura...

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Detalles Bibliográficos
Autores principales: Oriol-Tordera, Bruna, Berdasco, Maria, Llano, Anuska, Mothe, Beatriz, Gálvez, Cristina, Martinez-Picado, Javier, Carrillo, Jorge, Blanco, Julià, Duran-Castells, Clara, Ganoza, Carmela, Sanchez, Jorge, Clotet, Bonaventura, Calle, Maria Luz, Sánchez-Pla, Alex, Esteller, Manel, Brander, Christian, Ruiz-Riol, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410168/
https://www.ncbi.nlm.nih.gov/pubmed/32760119
http://dx.doi.org/10.1371/journal.ppat.1008678