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Laboratory assays reveal diverse phenotypes among microfilariae of Dirofilaria immitis isolates with known macrocyclic lactone susceptibility status

Prevention of canine heartworm disease caused by Dirofilaria immitis relies on chemoprophylaxis with macrocyclic lactone anthelmintics. Alarmingly, there are increased reports of D. immitis isolates with resistance to macrocyclic lactones and the ability to break through prophylaxis. Yet, there is n...

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Detalles Bibliográficos
Autores principales: Jesudoss Chelladurai, Jeba R. J., Martin, Katy A., Chinchilla-Vargas, Krystal, Jimenez Castro, Pablo D., Kaplan, Ray M., Brewer, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410292/
https://www.ncbi.nlm.nih.gov/pubmed/32760111
http://dx.doi.org/10.1371/journal.pone.0237150