Gene expression regulated by abatacept associated with methotrexate and correlation with disease activity in rheumatoid arthritis

OBJECTIVES: Abatacept acts as a competitive inhibitor of the CD28/(CD80/86) costimulation signal required for T cell activation. Mechanisms of action of abatacept have not been fully investigated. The objective of this study was to provide detailed insight into the mode of action of Abatacept based...

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Detalles Bibliográficos
Autores principales: Derambure, Céline, Dzangue-Tchoupou, Gaelle, D’Agostino, Maria Antonietta, Lequerré, Thierry, Vittecoq, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410313/
https://www.ncbi.nlm.nih.gov/pubmed/32760165
http://dx.doi.org/10.1371/journal.pone.0237143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410313/
https://www.ncbi.nlm.nih.gov/pubmed/32760165
http://dx.doi.org/10.1371/journal.pone.0237143

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