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Gene expression regulated by abatacept associated with methotrexate and correlation with disease activity in rheumatoid arthritis
OBJECTIVES: Abatacept acts as a competitive inhibitor of the CD28/(CD80/86) costimulation signal required for T cell activation. Mechanisms of action of abatacept have not been fully investigated. The objective of this study was to provide detailed insight into the mode of action of Abatacept based...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410313/ https://www.ncbi.nlm.nih.gov/pubmed/32760165 http://dx.doi.org/10.1371/journal.pone.0237143 |