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Protein tyrosine phosphatase 1B as a therapeutic target for Graves’ orbitopathy in an in vitro model
Graves’ orbitopathy (GO) is characterised in early stages by orbital fibroblast inflammation, which can be aggravated by oxidative stress and often leads to fibrosis. Protein tyrosine protein 1B (PTP1B) is a regulator of inflammation and a therapeutic target in diabetes. We investigated the role of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410323/ https://www.ncbi.nlm.nih.gov/pubmed/32760098 http://dx.doi.org/10.1371/journal.pone.0237015 |