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An extended and generalized framework for the calculation of metabolic intervention strategies based on minimal cut sets

The concept of minimal cut sets (MCS) provides a flexible framework for analyzing properties of metabolic networks and for computing metabolic intervention strategies. In particular, it has been used to support the targeted design of microbial strains for bio-based production processes. Herein we pr...

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Detalles Bibliográficos
Autores principales: Schneider, Philipp, von Kamp, Axel, Klamt, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410339/
https://www.ncbi.nlm.nih.gov/pubmed/32716928
http://dx.doi.org/10.1371/journal.pcbi.1008110