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The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

Mammalian Hedgehog (Hh) signaling plays key roles in embryogenesis and uniquely requires primary cilia. Functional analyses of several ciliogenesis-related genes led to the discovery of the developmental diseases known as ciliopathies. Hence, identification of mammalian factors that regulate cilioge...

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Detalles Bibliográficos
Autores principales: Yoshida, Saishu, Aoki, Katsuhiko, Fujiwara, Ken, Nakakura, Takashi, Kawamura, Akira, Yamada, Kohji, Ono, Masaya, Yogosawa, Satomi, Yoshida, Kiyotsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410489/
https://www.ncbi.nlm.nih.gov/pubmed/32758357
http://dx.doi.org/10.7554/eLife.57381