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The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis
Mammalian Hedgehog (Hh) signaling plays key roles in embryogenesis and uniquely requires primary cilia. Functional analyses of several ciliogenesis-related genes led to the discovery of the developmental diseases known as ciliopathies. Hence, identification of mammalian factors that regulate cilioge...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410489/ https://www.ncbi.nlm.nih.gov/pubmed/32758357 http://dx.doi.org/10.7554/eLife.57381 |