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Protective Role of Astrocyte-Derived Exosomal microRNA-361 in Cerebral Ischemic-Reperfusion Injury by Regulating the AMPK/mTOR Signaling Pathway and Targeting CTSB

BACKGROUND: Evidence has shown that microRNAs (miRNAs) are implicated in ischemic diseases. Therefore, the aim of the present study was to identify the functions of astrocyte (ATC)-derived exosomal miR-361 on cerebral ischemic-reperfusion (I/R) injury. METHODS: A rat model of cerebral I/R injury was...

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Detalles Bibliográficos
Autores principales: Bu, Xiancong, Li, Dong, Wang, Feng, Sun, Qimeng, Zhang, Zixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410492/
https://www.ncbi.nlm.nih.gov/pubmed/32801720
http://dx.doi.org/10.2147/NDT.S260748