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The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver
As the catalog of oncogenic driver mutations is expanding, it becomes clear that alterations in a given gene might have different functions and should not be lumped into one class. The transcription factor GATA3 is a paradigm of this. We investigated the functions of the most common GATA3 mutation (...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410826/ https://www.ncbi.nlm.nih.gov/pubmed/32587399 http://dx.doi.org/10.1038/s41388-020-1376-3 |