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Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis
Transglutaminase 2 (TG2), also known as tissue transglutaminase, is a calcium-dependent enzyme that has a variety of intracellular and extracellular substrates. TG2 not only increases in osteoarthritis (OA) tissue but also affects the progression of OA. However, it is still unclear how TG2 affects c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410847/ https://www.ncbi.nlm.nih.gov/pubmed/32764573 http://dx.doi.org/10.1038/s41598-020-70115-w |