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Transglutaminase-2 regulates Wnt and FoxO3a signaling to determine the severity of osteoarthritis

Transglutaminase 2 (TG2), also known as tissue transglutaminase, is a calcium-dependent enzyme that has a variety of intracellular and extracellular substrates. TG2 not only increases in osteoarthritis (OA) tissue but also affects the progression of OA. However, it is still unclear how TG2 affects c...

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Detalles Bibliográficos
Autores principales: Han, Min-Su, Jung, Youn-Kwan, Kim, Gun-Woo, Han, Seungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410847/
https://www.ncbi.nlm.nih.gov/pubmed/32764573
http://dx.doi.org/10.1038/s41598-020-70115-w