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Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons

In the central nervous system, hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are essential to maintain normal neuronal function. Recent studies have shown that HCN channels may be involved in the pathological process of ischemic brain injury, but the mechanisms remain unclear. A...

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Detalles Bibliográficos
Autores principales: Chen, Cheng, Liu, Li, Shu, Ya-Qiao, Jing, Ping, Lu, Yun, Zhang, Xiao-Xue, Zong, Xian-Gang, Guo, Lian-Jun, Li, Chang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410947/
https://www.ncbi.nlm.nih.gov/pubmed/32519067
http://dx.doi.org/10.1007/s12264-020-00513-7