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Production and purification of higher molecular weight chondroitin by metabolically engineered Escherichia coli K4 strains

The capsular polysaccharide obtained from Escherichia coli K4 is a glycosaminoglycan-like molecule, similar to chondroitin sulphate, that has established applications in the biomedical field. Recent efforts focused on the development of strategies to increase K4 polysaccharide fermentation titers up...

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Detalles Bibliográficos
Autores principales: D’ambrosio, S., Alfano, A., Cassese, E., Restaino, O. F., Barbuto Ferraiuolo, S., Finamore, R., Cammarota, M., Schiraldi, C., Cimini, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411012/
https://www.ncbi.nlm.nih.gov/pubmed/32764548
http://dx.doi.org/10.1038/s41598-020-70027-9