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Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity

The Eph family of receptor tyrosine kinases is crucial for assembly and maintenance of healthy tissues. Dysfunction in Eph signaling is causally associated with cancer progression. In breast cancer cells, dysregulated Eph signaling has been linked to alterations in receptor clustering abilities. Her...

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Detalles Bibliográficos
Autores principales: Ravasio, Andrea, Myaing, Myint Z., Chia, Shumei, Arora, Aditya, Sathe, Aneesh, Cao, Elaine Yiqun, Bertocchi, Cristina, Sharma, Ankur, Arasi, Bakya, Chung, Vin Yee, Green, Adrianne C., Tan, Tuan Zea, Chen, Zhongwen, Ong, Hui Ting, Iyer, N. Gopalakrishna, Huang, Ruby YunJu, DasGupta, Ramanuj, Groves, Jay T., Viasnoff, Virgile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411022/
https://www.ncbi.nlm.nih.gov/pubmed/32764731
http://dx.doi.org/10.1038/s42003-020-01136-4