Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties

Monanchoxymycalin C (MomC) is a new marine pentacyclic guanidine alkaloid, recently isolated from marine sponge Monanchora pulchra by us. Here, anticancer activity and mechanism of action was investigated for the first time using a human prostate cancer (PCa) model. MomC was active in all PCa cell l...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Kaune, Moritz, Kriegs, Malte, Hauschild, Jessica, Busenbender, Tobias, Shubina, Larisa K., Makarieva, Tatyana N., Hoffer, Konstantin, Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411023/
https://www.ncbi.nlm.nih.gov/pubmed/32764580
http://dx.doi.org/10.1038/s41598-020-69751-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411023/
https://www.ncbi.nlm.nih.gov/pubmed/32764580
http://dx.doi.org/10.1038/s41598-020-69751-z

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