Cargando…
Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
Monanchoxymycalin C (MomC) is a new marine pentacyclic guanidine alkaloid, recently isolated from marine sponge Monanchora pulchra by us. Here, anticancer activity and mechanism of action was investigated for the first time using a human prostate cancer (PCa) model. MomC was active in all PCa cell l...
Autores principales: | Dyshlovoy, Sergey A., Kaune, Moritz, Kriegs, Malte, Hauschild, Jessica, Busenbender, Tobias, Shubina, Larisa K., Makarieva, Tatyana N., Hoffer, Konstantin, Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411023/ https://www.ncbi.nlm.nih.gov/pubmed/32764580 http://dx.doi.org/10.1038/s41598-020-69751-z |
Ejemplares similares
-
Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020) -
Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022) -
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020) -
Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2018) -
Study of Structure–Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
por: Zhidkov, Maxim E., et al.
Publicado: (2022)