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Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines
Phenomic profiles are high-dimensional sets of readouts that can comprehensively capture the biological impact of chemical and genetic perturbations in cellular assay systems. Phenomic profiling of compound libraries can be used for compound target identification or mechanism of action (MoA) predict...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411054/ https://www.ncbi.nlm.nih.gov/pubmed/32764586 http://dx.doi.org/10.1038/s41598-020-69354-8 |