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ATIP3 deficiency facilitates intracellular accumulation of paclitaxel to reduce cancer cell migration and lymph node metastasis in breast cancer patients

Taxane-based chemotherapy is frequently used in neoadjuvant treatment of breast cancer patients to reduce tumor growth and lymph node metastasis. However, few patients benefit from chemotherapy and predictive biomarkers of chemoresistance are needed. The microtubule-associated protein ATIP3 has rece...

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Detalles Bibliográficos
Autores principales: Rodrigues-Ferreira, Sylvie, Nehlig, Anne, Kacem, Mariem, Nahmias, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411068/
https://www.ncbi.nlm.nih.gov/pubmed/32764625
http://dx.doi.org/10.1038/s41598-020-70142-7