Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy in highly malignant brain-tumors, glioblastomas (GBM), is limited. Here, we generate distinct imageable syngeneic mouse GBM-tumor models and utilize RNA-sequencing, CyTOF and correlative immunohistochemistry to...

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Detalles Bibliográficos
Autores principales: Khalsa, Jasneet Kaur, Cheng, Nina, Keegan, Joshua, Chaudry, Ameen, Driver, Joseph, Bi, Wenya Linda, Lederer, James, Shah, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411074/
https://www.ncbi.nlm.nih.gov/pubmed/32764562
http://dx.doi.org/10.1038/s41467-020-17704-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411074/
https://www.ncbi.nlm.nih.gov/pubmed/32764562
http://dx.doi.org/10.1038/s41467-020-17704-5

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