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Will Sirtuins Be Promising Therapeutic Targets for TBI and Associated Neurodegenerative Diseases?

Traumatic brain injury (TBI), a leading cause of morbidity worldwide, induces mechanical, persistent structural, and metabolic abnormalities in neurons and other brain-resident cells. The key pathological features of TBI include neuroinflammation, oxidative stress, excitotoxicity, and mitochondrial...

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Detalles Bibliográficos
Autores principales: Yang, Qianjie, Zhou, Yunxiang, Sun, Yuting, Luo, Yi, Shen, Ye, Shao, Anwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411228/
https://www.ncbi.nlm.nih.gov/pubmed/32848564
http://dx.doi.org/10.3389/fnins.2020.00791