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Will Sirtuins Be Promising Therapeutic Targets for TBI and Associated Neurodegenerative Diseases?
Traumatic brain injury (TBI), a leading cause of morbidity worldwide, induces mechanical, persistent structural, and metabolic abnormalities in neurons and other brain-resident cells. The key pathological features of TBI include neuroinflammation, oxidative stress, excitotoxicity, and mitochondrial...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411228/ https://www.ncbi.nlm.nih.gov/pubmed/32848564 http://dx.doi.org/10.3389/fnins.2020.00791 |