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MicroRNA-375 prevents TGF-β-dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathway
Transdifferentiation of lung fibroblasts to myofibroblasts is a crucial pathophysiological process in pulmonary fibrosis. MicroRNA-375 (miR-375) was initially identified as a tumor-suppressive factor, and its expression was negatively associated with the severity of lung cancer; however, its role an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411355/ https://www.ncbi.nlm.nih.gov/pubmed/32582987 http://dx.doi.org/10.3892/mmr.2020.11261 |