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MicroRNA-375 prevents TGF-β-dependent transdifferentiation of lung fibroblasts via the MAP2K6/P38 pathway

Transdifferentiation of lung fibroblasts to myofibroblasts is a crucial pathophysiological process in pulmonary fibrosis. MicroRNA-375 (miR-375) was initially identified as a tumor-suppressive factor, and its expression was negatively associated with the severity of lung cancer; however, its role an...

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Detalles Bibliográficos
Autores principales: Zhang, Xinghua, Chen, Qian, Song, Hengya, Jiang, Wanli, Xie, Songping, Huang, Jie, Kang, Ganjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411355/
https://www.ncbi.nlm.nih.gov/pubmed/32582987
http://dx.doi.org/10.3892/mmr.2020.11261