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Shikonin inhibits CEBPD downregulation in IL-17-treated HaCaT cells and in an imiquimod-induced psoriasis model

Psoriasis is a chronic inflammatory skin disease characterized by well-defined scaly papules and plaques. Interleukin (IL)-17 is involved in its pathogenesis and promotes the proliferation of epidermal keratinocytes through signal transducer and activator of transcription 3 (STAT3) activation. Shiko...

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Detalles Bibliográficos
Autores principales: Lan, Xiao-Ou, Wang, He-Xiao, Qi, Rui-Qun, Xu, Yuan-Yuan, Yu, Ya-Jie, Yang, Yang, Guo, Hao, Gao, Xing-Hua, Geng, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411367/
https://www.ncbi.nlm.nih.gov/pubmed/32705251
http://dx.doi.org/10.3892/mmr.2020.11315