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Trimetazidine improves hepatic lipogenesis and steatosis in non-alcoholic fatty liver disease via AMPK-ChREBP pathway

Clinical studies have demonstrated that trimetazidine (TMZ) possesses a synergistic hypolipidemic effect together with statins, but the underlying mechanism remains to be elucidated. The present study aimed to investigate the role of TMZ in non-alcoholic fatty liver disease (NAFLD). By investigating...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Li, Can, Li, Xiuqi, Wu, Cheng, Zhou, Haiyan, Lu, Shuang, Liu, Xingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411376/
https://www.ncbi.nlm.nih.gov/pubmed/32705195
http://dx.doi.org/10.3892/mmr.2020.11309