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Trimetazidine improves hepatic lipogenesis and steatosis in non-alcoholic fatty liver disease via AMPK-ChREBP pathway
Clinical studies have demonstrated that trimetazidine (TMZ) possesses a synergistic hypolipidemic effect together with statins, but the underlying mechanism remains to be elucidated. The present study aimed to investigate the role of TMZ in non-alcoholic fatty liver disease (NAFLD). By investigating...
Autores principales: | Zhang, Ying, Li, Can, Li, Xiuqi, Wu, Cheng, Zhou, Haiyan, Lu, Shuang, Liu, Xingde |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411376/ https://www.ncbi.nlm.nih.gov/pubmed/32705195 http://dx.doi.org/10.3892/mmr.2020.11309 |
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