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Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a severe interstitial disease with a mean survival of about 2.5–5 years after diagnosis. Its pathophysiology is still a major challenge for science. It is known that angiotensin II (Ang-II) binds AT1 receptor (AT1R) and its overactivation induces fibrosis, infl...

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Detalles Bibliográficos
Autores principales: Raupp, Débora, Fernandes, Renata Streck, Antunes, Krist Helen, Perin, Fabíola Adélia, Rigatto, Katya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411382/
https://www.ncbi.nlm.nih.gov/pubmed/32777324
http://dx.doi.org/10.1016/j.peptides.2020.170384