Combined administration of SHP2 inhibitor SHP099 and the α7nAChR agonist PNU282987 protect mice against DSS-induced colitis

Inflammatory bowel disease (IBD) is a chronic inflammatory condition with complex pathogenesis that currently has no cure. α7 nicotinic acetylcholine receptor (α7nAChR) is known to regulate multiple aspects of immune function. The present study aimed to evaluate the protective effects of PNU282987 a...

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Detalles Bibliográficos
Autores principales: Xiao, Junhua, Zhang, Gufang, Gao, Sujun, Shen, Jiaqing, Feng, Huang, He, Zhilong, Xu, Chunfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411392/
https://www.ncbi.nlm.nih.gov/pubmed/32705242
http://dx.doi.org/10.3892/mmr.2020.11324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411392/
https://www.ncbi.nlm.nih.gov/pubmed/32705242
http://dx.doi.org/10.3892/mmr.2020.11324

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