Wild-type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells

Glioblastoma (GBM) is the most common type of brain cancer and has the highest mortality. Dysregulated expression of wild-type isocitrate dehydrogenase 1 (IDH1) has been demonstrated to promote the progression of primary GBM without accumulating D-2-hydroxyglutarate, which differs from IDH1 mutation...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Xiaopeng, Wu, Shen, Zhang, Jingyi, Li, Meng, Xu, Feng, Wang, Ao, Lei, Yang, Zhu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411459/
https://www.ncbi.nlm.nih.gov/pubmed/32705169
http://dx.doi.org/10.3892/mmr.2020.11250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411459/
https://www.ncbi.nlm.nih.gov/pubmed/32705169
http://dx.doi.org/10.3892/mmr.2020.11250

Ejemplares similares