Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts

The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic anemia. PIEZO1 expression is not limited to er...

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Detalles Bibliográficos
Autores principales: Aglialoro, Francesca, Hofsink, Naomi, Hofman, Menno, Brandhorst, Nicole, van den Akker, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411472/
https://www.ncbi.nlm.nih.gov/pubmed/32848880
http://dx.doi.org/10.3389/fphys.2020.00958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411472/
https://www.ncbi.nlm.nih.gov/pubmed/32848880
http://dx.doi.org/10.3389/fphys.2020.00958

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