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Protective effects of catalpol on mitochondria of hepatocytes in cholestatic liver injury

Cholestasis, which is caused by the obstruction of bile flow, can lead to rapid organ injury, cell apoptosis and necrosis of hepatocytes, and may eventually develop into fibrosis and cirrhosis. Oxidative stress and mitochondrial dysfunction are the key pathogenic signs of hepatic cholestasis. Catalp...

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Detalles Bibliográficos
Autores principales: Gao, Xingjuan, Xu, Jiaju, Liu, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411478/
https://www.ncbi.nlm.nih.gov/pubmed/32705256
http://dx.doi.org/10.3892/mmr.2020.11337