microRNA-99a Restricts Replication of Hepatitis C Virus by Targeting mTOR and De Novo Lipogenesis

In this study, we investigated the role of microRNA-99a (miR-99a) in hepatitis C virus (HCV) replication and lipogenesis in hepatocytes. Cell-culture-derived HCV (HCVcc) infection caused down-regulation of miR-99a in Huh-7 cells, and the relative levels of miR-99a were significantly lower in the ser...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Eun Byul, Sung, Pil Soo, Kim, Jung-Hee, Park, Dong Jun, Hur, Wonhee, Yoon, Seung Kew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411587/
https://www.ncbi.nlm.nih.gov/pubmed/32605105
http://dx.doi.org/10.3390/v12070696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7411587/
https://www.ncbi.nlm.nih.gov/pubmed/32605105
http://dx.doi.org/10.3390/v12070696

Ejemplares similares